Myasthenia Gravis: An unusual case report with rare presentation
Myasthenia Gravis
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1.
Sotiropoulou A. Myasthenia Gravis: An unusual case report with rare presentation. Neurons [Internet]. 30 juni 2020 [citerad 29 december 2024];2(1):7-9. Tillgänglig vid: https://cmrasociety.org/neurons/index.php/nu/article/view/11

Abstract

Introduction

Myasthenia gravis (MG) is part of a continuum of autoimmune diseases that damage neuromuscular junctions by anti-acetylcholine receptor antibodies. It is a relatively rare disease with a greater prevalence in women. The classical presentation is diplopia or ptosis fluctuating and, uncommonly, dysphagia or dysphonia. While this condition is rare, it can affect any muscle, including the muscles of the neck or of the proximal limb. No documented cases of MG exhibiting as isolated neck weakness.

Case presentation

A 72-year-old female patient had neck weakness associated with a slight pain that intensified gradually during the day. Examination indicates only reduced tension of the cervical muscle motor strength. Anti-acetylcholine receptor antibodies The anti-acetylcholine receptor binding antibody was 14.07 nmol / L, 57 per cent blocking antibody, and 78 per cent modulating antibody, which is consistent with a myasthenia gravis diagnosis. The patient was prescribed Regonol, which improved her neck weakness. The patient was followed up, she returned to her previous baseline lifestyle with no clinical complications.

Conclusion

MG usually occurs in middle-aged female populations but can rarely also occur in elderly people with atypical symptoms. Clinicians should have a high index of myasthenia suspicion showing fatigued muscle exhaustion to minimize investigation costs and morbidity.

https://doi.org/10.5281/zenodo.4038235
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