Effect of advancing age on pulmonary functions in petrol pump workers of Cuttack : a cross sectional study
Main Article Content
Abstract
Background
Environmental pollution is a worldwide phenomenon. Petrol pump workers are exposed to toxic substances present in petrol and diesel and also to various air pollutants. Long term exposure of these chemical vapours leads to deleterious effects on respiratory functions that range from mild cough to lung cancer. In the present study an attempt has been made to find out the correlation of advancing age and toxic effects of vapours on respiratory system by comparing pulmonary function tests in petrol pump workers and subjects not exposed to petrol.
Methods
The study comprised of 60 petrol pump workers in age group 30-60 years working for more than 1 year. 60 healthy age matched male served as controls. Age, smoking habits, duration of exposure and health conditions of each subject were recorded. The pulmonary function was assessed in all subjects by Medspiror having Helios 401 software. The pulmonary function parameters studied were FVC, FEV1, FEV1/FVC ratio, FEF25-75%, PEFR and MVV. The parameters were compared by using Student’s t-test, ANOVA and multiple comparison Bonferroni tests.
Results
A statistically significant decline in FEV1, FVC, PEFR, FEF25-75% and MVV was observed in petrol pump workers with advancing age. However, decline in FEV1/FVC was significant in elderly age of 50 to 60 years.
Conclusion
Elder workers were more susceptible to harmful effects of benzene and other gaseous pollutants on pulmonary functions. Early recognition and removal of susceptible workers from work place before chronic impairment develops will prove to be beneficial.
Article Details
References
Zhu Y, Hinds WC, Kim S, Sioutas C, Concentration and size distribution of ultrafine particles near a major highway. J Air Waste Manag Assoc. 2002 ;52(9):1032-42.
Chena Y, Ebensteinb A, Greenstonec M, Lie H. Evidence on the impact of sustained exposure to air pollution on life expectancy from China’s Huai River policy. PNAS. 2013; 110(32):1-6.
Wong CM, Vichit-Vadakan N, Vajanapoom N, Ostro B, Thach TQ, Chau PY et al. Part 5. Public health and air pollution in Asia (PAPA): a combined analysis of four studies of air pollution and mortality. Res Rep Health Eff Inst. 2010;(154):377-418.
Chung KF, Zhang J, Zhong N. Outdoor air pollution and respiratory health in Asia. Respirology. 2011;16(7):1023-26.
Hillerdal G, Nõu E.Occupation and bronchial carcinoma. Scand J Respir Dis. 1979;60(2):76-82.
Jedrychowski W, Becher H, Wahrendorf J, Flak E, Basa-Cierpiałek Z. Combined effects of tobacco smoking, occupational factors and atmospheric air pollution as risk factors of bronchial carcinoma. Results of retrospective studies in Cracow. Nowotwory. 1989;39(2):65-75.
Sadiqua Begum, MB Rathna. Pulmonary function tests in petrol filling workers in Mysore city Pak J Physiol 2012;8(1):12-14.
Madhuri BA, Chandrashekar M, Kondam A, Qairunnisa S, Suresh M, Lalitha A. A study on pulmonary function test in petrol pump workers in kanchepuram population. Int J Biol Med Res. 2012; 3(2):1712-14.
Salvi S, Blomberg A, Rudell B, Kelly F, Sandstorm T, Holgate ST. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am J Respir Crit Care Med. 199; 159(3):702–09.
What Is COPD? Accessed on 10-6-2014 from URL: http://www.nhlbi.nih.gov/health/health-topics/topics/copd/printall-index.html
Sharma G, Goodwin J. Effect of aging on respiratory system physiology and immunology. Clin Interv Aging. Sep 2006; 1(3):253–60.
Kelly FJ. Air pollution and the elderly:oxidant/antioxidant issues with consideration. Eur.Respir J Suppl,40:70-75s.
Anderson HR, Atkinson RW, Bremner SA, et al. Particulate air pollution and hospital admissions for cardiorespiratory diseases: are the elderly at greater risk? Eur Respir J Suppl 2003;40:39s–46s.
Aga E, Samoli E, Touloumi G, Anderson HR, Cadum E, Forsberg B et al. Short-term effects of ambient particles on mortality in the elderly: results from 28 cities in the APHEA2 project. Eur Respir J Suppl 2003;40:28s – 33s.
Jaakkola MS. Environmental tobacco smoke and health in the elderly. Eur Respir J 2002;19(1):172–81.
W. M. Wahba Influence of Aging on Lung Function-Clinical Significance of Changes from Age Twenty. Anesth Analg. 1983;62(8):764-76.
M L Burr, K M Phillips and D N Hurst. Lung functions in elderly; Thorax 1985; 40(1): 54-59.
Mittman C, Edelman NH, Norris AH, et al. 1965. Relationship between chest wall and pulmonary compliance with age. J Appl Physiol, 20:1211-16.
Arora NS, Rochester DF. Effect of body weight and muscularity on human diaphragm muscle mass, thickness, and area. J Appl Phsiol 1982;52(1):64– 70.
McClaran SR, Babcock MA, Pagelow DF, Reddan WG, Dempsey JA. Longitudinal effects of aging on lung function at rest and exercise in healthy active fit elderly adults. J Appl Physiol(1985), 78(5):1957-68.
Wichmann HE. Diesel exhaust particles. Inhal Toxicol 2007; 19 Suppl 1:241-44.
Pinkerton KE, Green FH, Saiki C, Vallyathan V, Plopper CG, Gopal V et al. Distribution of particulate matter and tissue remodeling in human lung.Environ Health Perspect 2000;108(11):1063-69.
Singhal M, Khaliq F, Singhal S, Tandon OP. Pulmonary functions in petrol pump workers: a preliminary study. Indian J Physiol Pharmacol. 2007; 51(3):244-48.
Ren WY, Li L, Zhao RY, Zhu L. Age-associated changes in pulmonary function: a comparison of pulmonary function parameters in healthy young adults and the elderly living in Shanghai. Chin Med J (Engl). 2012;125(17):3064-68.
Udwalia F.E, Shetye V.M. The Maximum expiratory flow volume curve in normal subjects in India. Chest Journal. 1986; 89(6)852-56.
Moorman WJ, Clark JC, Pepelko WE, Mattox J. Pulmonary function responses in cats following long-term exposure to diesel exhaust. J Appl Toxicol 1985; 5(5): 301–5.
McFadden ER, Linden DA. A reduction in the maximum mid expiratory flow rate. A spirographic manifestation of small airway disease. Am J Med 1972; 52(6):725–27.
Levsen K. The analysis of diesel particulate. Fresenius Z Anal Chem; 1988; 331: 467–