Clear cell sarcoma of ovary - an exceedingly unusual neoplasm

Abstract

Dear Sir,

Clear Cell Sarcomas are uncommon neoplasm of childhood seen mostly in kidneys. Most of these tumors are aggressive with an unfavorable histology. These Tumors are mostly seen in kidneys where they have a strong propensity to metastasize to bone. Tumors with similar histology are very rarely described in other organs. There is a single case report of Clear Cell Sarcoma involving ovaries. We herein report second case of this rare entity. We report a very unusual case of Clear Cell Sarcoma of ovary in an eight month old baby girl who was admitted to Jeevan Jyoti Hospital Bareilly, with chief complaints of abdominal distention. USG examination revealed a solid right ovarian mass with moderate ascites. Her CA 125 levels were raised 274.8 u/ml. Her CEA and AFP levels were normal 0.6 ng/ml and 5.36 ng/ml respectively. Ascitic fluid cytology done was negative for malignant cells. Her other hematological investigations and Serum Creatinine, Na, K, Calcium levels were normal (0.72 mg/dl, 141mmol/L, 4.19 mmol/L and 10.0 mg/dl respectively). Based on these investigations unilateral salpingo-oophorectomy was performed. Grossly received in formalin is a right ovarian mass measuring 4 x 3 x 1.5 cms. Cut surface was solid yellowish.